Dr Marc C Kimber
Department of Chemistry
Senior Lecturer in Organic Chemistry
Research Interests include total synthesis, catalysis utilising organometallics and the use of chiral cleft molecules for molecular recognition and catalysis.
Background
Marc grew up in Tea Tree Gully in Adelaide, South Australia. He attended Rostrevor College and subsequently did his undergraduate at the University of Adelaide in chemistry and genetics. He stayed at UoA for his postgraduate studies and obtained his PhD in chemistry 1999. He then held postdoctoral positions at the Universities of Sydney (Prof. M. M. Harding), Adelaide (Prof. D. K. Taylor) and Nottingham (Prof. J. S. Clark and Prof. C. J. Moody). He was appointed to his first independent academic position as Lecturer in Organic Chemistry at Loughborough in September 2008, and was subsequently promoted to Senior Lecturer in 2015.
Access Marc's Research Gate profile here.
Research Area
Marc’s main research focus is in the development of new synthetic transformations and strategies and their applicability in the synthesis of natural products and metabolites of biological relevance. His role within the TCB is to investigate novel and efficient synthetic routes to natural products and metabolites with anti-inflammatory activity. These targets include the Resolvin E- and D-series, and the furan fatty acids (FFA’s).
Access Marc's research group website here.
Current Funding
EPSRC (EP/M027341/1) Tackling Antimicrobial Resistance: An Interdisciplinary Approach. (NB: not aligned with TCB).
Republic of Iraq Ministry of Higher Education: Synthesis of xanthanolide anti-inflammatory agents.
Relevant Publications
‘A simple one-pot preparation of N-allenyl amides, ureas, carbamates and sulfonamides using a DMSO/tBuOK protocol’ Bousfield, T. W.; *Kimber, M. C. Tetrahedron Letts. 2015, 56, 350.
‘The Au(I) Catalyzed Activation of Allenamides and Their Subsequent Transformation into Chromanes: A Method for the Regiocontrolled Addition to the α- and γ-Positions of the Allene Unit’ Slater, N. H.; Brown, N. J.; Elsegood, M, R, J.; *Kimber, M. C. Org. Lett. 2014, 16, 4606.
‘The regioselective outcome of ring rearrangement metathesis transformations performed on bicyclo[2.2.2]oct-2-ene derivatives’ Standen, P. E.; *Kimber, M. C. Tetrahedron Lett. 2013, 54, 4098.
‘An Asymmetric Synthesis of trans-Fused Butyrolactones from Endoperoxides’ Priest, J.; Longland, M. R.; Elsegood, M. R. J.; *Kimber, M. C. J. Org. Chem. 2013, 78, 3476.
‘An Au(I) catalysed allenamide cyclisation giving access to a α-vinyl substituted tetrahydroisoquinoline building block’ Singh. S.; Elsegood, M. R. J.; *Kimber, M. C. Synlett 2012, 565.
‘Total Synthesis of the Marine-Derived Cyclic Depsipeptide Alternaramide’ Horton, A. E.; May, O, S.; Elsegood, M. R. J.; *Kimber, M. C. Synlett 2011, 797.
‘An Intermolecular Hydroamination of Allenamides with Arylamines Catalyzed by Cationic Au(I) Salts’ Hill, A. W.; Elsegood, M. R. J.; *Kimber, M. C. J. Org. Chem. 2010, 75, 5406.
‘A Facile and Mild Synthesis of Enamides Using Gold Catalyzed Addition to Allenamides’ *Kimber, M. C. Org. Lett. 2010, 12, 1128.