Background

Luke graduated with a Bsc Sport & Exercise Science from Nottingham Trent University. Further education lead him to complete an Msc Sport & Exercise Nutrition at Loughborough University. During his project, Luke investigated the effects of Omega-3 fatty acids on lipid metabolism and mitochondrial biogenesis utilizing in-vitro skeletal muscle models. Luke then undertook his PhD in the TCB Research Group, starting in April 2015. In his spare time you will find him on the roof of the new NCESM building playing table tennis!

His PhD is part of the Translational Chemical Biology Research Group (TCB) investigating the effects of PUFA’s and their synthetic derivatives on inflammatory resolution in skeletal muscle, supervised by Prof. Mark Lewis along with Dr. Martin Lindley & Dr. Gareth Pritchard.

Project Information

The use of Synthetic Compounds for the resolution of inflammation in skeletal muscle

Current research looks to establish a model of inflammatory signaling in skeletal muscle in-vitro. Alongside this, research looks to investigate the role of PUFA’s in inflammatory signaling pathways in various cell types. Following on from this, research will be directed towards the investigation of lipid derived mediators, their biological activity and role in inflammatory signaling and lipid oxidation on a cellular level.

Currently

Luke is a Researcher in the School of Health Sciences at Leicester University email : lab69@le.ac.uk

Baker, L.A., Martin, N.R.W., Kimber, M.C., Pritchard, G.J., Lindley, M.R. and Lewis, M.P. (2018). Resolvin E1 (Rv E1) attenuates LPS induced inflammation and subsequent atrophy in C2C12 myotubes. J Cell Biochem. Jul;119(7):6094-6013.