Background

Bethan completed a degree in Human Biology with First Class Honours at Loughborough University in 2014, with a Diploma in Professional studies. The diploma was awarded for a one year industrial placement completed at Abbott Diabetes Care during her third year of studies. In her undergraduate final year, Bethan researched the genetic association between a SNP (rs531564) in a gene coding for microRNA hsa-miR-142a and Type 2 Diabetes Mellitus. The postgraduate research Bethan is undertaking is part of the Translational Chemical Biology Mini-Centre for Doctoral Training which aims to assess the “Chemical Synthesis and biological evaluation of novel naturally informed anti-inflammatory agents”. Bethan is co-supervised by Dr Sarabjit Mastana (SSEHS), Dr Martin Lindley (SSEHS) and Dr Jim Reynolds (Department of Chemistry).

Project Information

Epigenetic impact and mechanistic evaluation of bioactive lipid derived mediators

• Measurement of biological activity of inflammatory mediators from cell culture work.

• Association and impact of genetic polymorphism on biological activity.

• Assessment of the epigenetic impact of lipid derived mediators.

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Funding

Bethan has received funding from:

• The National Institute of Health Research (NIHR) Collaboration for Leadership in Applied Health Research and Care East Midlands (CLAHRC EM). 

• Loughborough University Health & Wellbeing Research Challenge Fund

• Silver Sponsorship from Primerdesign